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PROTECTION AGAINST ENDOCRINE DISRUPTORS

Projects

Projects

Project Title

Project Brief

ESR

Supervisors

PrimaryCo-Supervisor
Consumer perception of endocrine disruptors in the environment and food chain. Exploring consumer perceptions and understanding of EDs in in the environment and food chain for the development of efficient risk communication strategies. 1  Prof Dean Prof Connolly
Identifying mixtures of contaminants associated with adverse child health outcomes. Utilising epidemiological data to identify mixtures of contaminants associated with adverse child health outcomes. 2  Prof Eggesbo  Dr Mandal
Health impacts of complex mixtures on human foetal and placental health. Investigating the health impacts of complex chemical mixtures on human foetal and placental health. Prof Fowler  Prof Connolly
Mycotoxins, mass spectrometry, farm animals, health effects. Determining farm animal exposure to a large number of mycotoxins. 4   Prof Elliott Prof Connolly 
In vivo zebrafish larvae tests on endocrine disruptors and mixtures. Zebrafish larvae tests for the study of ED mixture effects on early development and behaviour and gene regulation events, especially in the brain. 5  Dr Muller  Dr Eriksen
Effect of zearalenone, an oestrogenic mycotoxin, alone or in combination, on the intestine. The effects of the mycotoxin Zearalenone and co-occurring mycotoxin mixtures on the function of the intestine. 6  Dr Oswald  Prof Eggesbo 
Effects of defined realistic ED mixtures on gut microbiota composition, neurodevelopment, and behaviour in mice. The effects of defined realistic ED mixtures on gut microbiota composition, neurodevelopment and behaviour in mice. 7 
Dr Verhaegen
Prof Connolly
Exposure effects of defined realistic mixtures of POPs on zebrafish development, behaviour, and population. Exposure effects of ED and realistic mixtures in Zebrafish models. Behavioural outcomes, combined with morphology and transcriptomics studies will be used to investigate exposure effects on neurodevelopment, immune function and their interactions. 8 
Dr Verhaegen
Prof Fowler 
Aryl hydrocarbon receptor transactivation assays to study health impacts of exposure to mixtures of chemicals. Assessing the impact of exposure to mixtures of chemicals found in drinking water on the Aryl hydrocarbon receptor. 9  Prof Scippo  Prof Connolly
 
Endocrine disruptor compounds in cyanobacteria. Screening cyanobacteria for ED activity. 10  Dr Uhlig  Dr Kausel
QSAR modelling EDs and their mixtures. Development of predictive QSAR models for ED mixtures 11  Dr Gozalbes  Prof Eggesbo 
In vivo biomarker assays in adult carp. Development of non-invasive assays to assess in vivo biomarkers in fish. 12  Dr Kausel  Dr Muller
Emerging High Content Analysis technology for the investigation of EDs & their mixtures. Development of state-of-the-art HCA assays for the investigation of EDs and their mixture effects on cellular health and disease pathways. 13   Dr Connolly Prof Ropstad
Development of a combined chemical-biological detection system for mycotoxin/POP mixtures affecting human development. Development of a combined chemical-biological detection system for ED mixtures affecting human development. 14  Dr Van der Burg   Prof Connolly
Development of a combined chemical-biological detection system for mycotoxin mixtures affecting animal health. Development of a combined chemical-biological detection system for ED mixtures affecting animal reproduction. 15  Dr Van der Burg  Dr Eriksen